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A cloned child?
The first human clone, a healthy 7-pound girl named Eve, was born the 26th
of December 2002, according to Clonaid, a private company linked to the
Raelian religious sect.
While it offered no scientific evidence the birth actually took place, the
claim that it engineered such a feat opened a
floodgate of debate on Friday over reproductive technologies such as
cloning by nuclear transfer and currently accepted IVF.
The cloning event occurred because the husband of the couple concerned was
infertile.
Identical twins are genetically identical clones that occur naturally,
except that they are the same age, while a nuclear transfer clone is
obviously conceived as a baby.
The company was in a race with two other groups, headed by Dr. Antinori
and Dr. Zavos, to see who could produce a cloned child first.
Clonaid hopes to have 20 more births in 2003. They said the first of those
is due to be born next week in Europe to a North American couple, followed
by three other babies to two Asian couples and a lesbian couple.
During a hastily arranged news conference on Friday 27th December 2002 in
Hollywood U.S., Brigitte Boisselier, CEO of Clonaid, a company founded in
1997 in the Bahamas, said Eve was born at 11:55 a.m. on Thursday 26th
December by Caesarean section.
Boisselier said proof that Eve is a genetic replica of her 31-year-old
American mother would come after an independent expert visits the mother
and child next week to collect DNA samples, which will be taken to an
independent lab for testing. The results should be available within nine
days, she said.
Boisselier said "the parents are happy", that the child is healthy and
urged the media not to treat the baby as "a monster" or "something that is
disgusting."
Scientists expressed strong doubts while religious leaders voiced outrage,
calling it, among other things, morally wrong.
Freelance reporter and physicist Dr. Michael Guillen, a former ABC News
science editor, will coordinate the genetic tests using a medical expert
of his choosing and an independent lab. He is not being paid by Clonaid
and has said he would make the findings public when the analysis is
finished.
"Scientists make all kinds of claims and often there's no substantiation.
I just want to have independent scientists evaluate it," said Guillen, who
has been writing about cloning since 1997 and who is paying his own
expenses to verify the results.
In human cloning, the nucleus of a human egg is removed and replaced with
the nucleus of a human cell. The egg then grows into an embryo, using the
donor's genes, and is planted in a womb.
To create Eve, the nucleus of a skin cell from the mother was implanted in
her egg, Boisselier said, providing the DNA match. She noted this
procedure did not take place in the United States, although she did not
say where it occurred.
She said the fact the press conference was held in Hollywood beach in the
U.S. had nothing to do with the location of the birth.
Boisselier said Eve and her mother, whose name she did not disclose,
were
in a hospital and would go home Monday. She said Eve's parents are U.S.
citizens who have an older daughter from the wife's previous marriage. The
husband is infertile.
No U.S. laws directly prohibit human cloning. The Republican House in June
approved a bill banning human cloning, but the Senate did not follow suit,
fearing a total ban would hurt the potential for advancing medical
research.
Clonaid began experimenting with human eggs in January of this year and
"had really good success really quickly," Boisselier said.
Of 10 total implantations in this first round, five women miscarried, she
added.
Two other groups also are trying to clone a human, one headed by Dr.
Zavos
and the other headed up by Severino Antinori, an Italian fertility doctor
who in 1994, Antinori helped a 62-year-old woman become pregnant by
implanting a donor's fertilized egg in her uterus.
After Dolly, the sheep, was successfully cloned in 1996, Rael, founder of
the Raelians, created Clonaid as a private, for-profit firm dedicated to
cloning research.
After the Bahamanian government made cloning illegal, the group moved to
an undisclosed U.S. location. The company also has a subsidiary in South
Korea, although the government there is moving to make cloning research
illegal.
The company's main funding was $500,000 from Mark Hunt, a West Virginia
lawyer and former legislator. In 2001, he and his wife asked Clonaid to
clone their 10-month-old son, who had died two years earlier. He has since
severed ties with the company.
That year, FDA officials visited Clonaid's West Virginia lab and ordered
all cloning experiments to stop, spokeswoman Lenore Gelb said.
Boisselier identifies herself as a Raelian "bishop" and said the group's
leader, Rael, put her in charge of the cloning operation several years
ago. She also is the mother of a 22-year-old daughter, who Boisselier
hopes will become a surrogate mother.
Boisselier claims to possess two chemistry degrees but said she is not a
specialist in reproductive medicine. She said Clonaid retains
philosophical but not economic links to the Raelians.
If clonaid's claim to have produced a healthy cloned child is
substantiated by genetic tests, then it will offer the somewhat
controversial option to other infertile couples, who IVF can not help, to
conceive a biologically related child.
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